Data

Year of publication

2020

Type

Quantitative

Design

Longitudinal

Classification

NOVA

Country studied

France

Data

Secondary

Data Collected

Three 24 hours recalls

Study setting

Household

Age group of participant

Adults/18+

Participant sex

Mixed

Target population

General

Sample size

n=110,260 (participants)

Ultra-processed food intake in association with BMI change and risk of overweight and obesity: A prospective analysis of the French NutriNet-Santé cohort/PLoS Med

Goal

Investigate the associations between UPF consumption and the risk of overweight and obesity, as well as change in body mass index (BMI).

Results

After adjusting for age, sex, educational level, marital status, physical activity, smoking status, alcohol intake, number of 24-hour dietary records, and energy intake, we observed a positive association between UPF intake and gain in BMI (β Time × UPF = 0.02 for an absolute increment of 10 in the percentage of UPF in the diet, P < 0.001). UPF intake was associated with a higher risk of overweight (n = 7,063 overweight participants; hazard ratio (HR) for an absolute increase of 10% of UPFs in the diet = 1.11, 95% CI: 1.08–1.14; P < 0.001) and obesity (n = 3,066 incident obese participants; HR10% = 1.09 (1.05–1.13); P < 0.001). These results remained statistically significant after adjustment for the nutritional quality of the diet and energy intake. Study limitations include possible selection bias, potential residual confounding due to the observational design, and a possible item misclassification according to the level of processing. Nonetheless, robustness was tested and verified using a large panel of sensitivity analyses.

Authors

Beslay M, Srour B, Méjean C, Allès B, Fiolet T, et al.

Journal

DOI