Data

Year of publication

2018

Type

Qualitative

Design

Narrative

Classification

NOVA

Country studied

Global

Data

Secondary

Data Collected

Literature

Study setting

N/A

Age group of participant

N/A

Participant sex

N/A

Target population

N/A

Sample size

N/A

The Western Diet–Microbiome-Host Interaction and Its Role in Metabolic Disease

Goal

Review factors and potential mechanisms related to diet and metabolic disease in the gut microbiome, more specifically impact of ultra-processed food in promoting inflammation-related processes through diet-microbiome-host interactions.

Results

We argue that the Western diet promotes inflammation that arises from both structural and behavioral changes in the resident microbiome. The environment created in the gut by ultra-processed foods, a hallmark of the Western diet, is an evolutionarily unique selection ground for microbes that can promote diverse forms of inflammatory disease. Recognizing the importance of the microbiome in the development of diet-related disease has implications for future research, public dietary advice as well as food production practices. Research into food patterns suggests that whole foods are a common denominator of diets associated with a low level of diet-related disease. Hence, by studying how ultra-processing changes the properties of whole foods and how these foods affect the gut microbiome, more useful dietary guidelines can be made. Innovations in food production should be focusing on enabling health in the super-organism of man and microbe, and stronger regulation of potentially hazardous components of food products is warranted.

Authors

Zinöcker M, Lindseth I.

Journal

Nutrients

DOI