Year of publication
Three 24 hours recalls
Age group of participant
Prospective association between ultra-processed food consumption and incident depressive symptoms in the French Nutri-Net./BMC Medicine
Investigate for the first time the prospective association between %UPF in the diet and the risk of depressive symptoms using the data of the NutriNet-Santé cohort study.
Over a mean follow-up of 5.4 years, 2221 incident cases of depressive symptoms were identified. After accounting for a wide range of potential confounders, an increased risk of depressive symptoms was observed with an increased %UPF in the diet. In the main model adjusted for sociodemographic characteristics, body mass index, and lifestyle factors, the estimated hazard ratio for a 10% increase in UPF was 1.21 (95% confidence interval = 1.15–1.27). Considering %UPF in food groups, the association was significant only for beverages and sauces or added fats. Overall, UPF consumption was positively associated with the risk of incident depressive symptoms, suggesting that accounting for this non-nutritional aspect of the diet could be important for mental health promotion.
Adjibade M, Julia C, Allés B, Touvier M, Lemogne C, Srour B, Hercberg, Galan P, Assmann K, Kesse-Guyot E.