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Old fashioned vs. ultra-processed-based current diets: possible implication in the increased susceptibility to type 1 diabetes and celiac disease in childhood
Review implications of ultra-processed products-based diet and its components, in relation with gut microbiota alterations and susceptibility to autoimmunity for celiac disease and type 1 diabetes in childhood.
The nutritional composition of ultra-processed foodstuffs can induce gut dysbiosis, promoting a pro-inflammatory response and consequently, a “leaky gut”. These factors have been associated with increased risk of autoimmunity in genetically predisposed children. In contrast, unprocessed and minimally processed food-based diets have shown the capacity to promote gut microbiota eubiosis, anti-inflammatory response, and epithelial integrity, through bacterial butyrate production.
Aguayo-Patron SV, Caleron de la Barca, AM.