Data

Year of publication

2020

Type

Quantitative

Design

Cross-sectional

Classification

Other

Country studied

Mexico

Data

Primary

Data Collected

One food frequency

Study setting

Clinic

Age group of participant

Adults/18-50

Participant sex

Mixed

Target population

Vulnerable

Sample size

n=27 (participants)

Hypercholesterolemia associated with erythrocytes morphology assessed by scanning electron microscopy in metabolically unhealthy individuals with normal-weight and obesity./Obesity Medicine

Goal

Associate hypercholesterolemia and obesity with red blood cell (RBC) morphology as assessed by scanning electron microscopy (SEM) in metabolically healthy and unhealthy adults with normal weight and with obesity.

Results

SEM images showed altered RBC morphologies in the MUNW, MHO, and MUO groups. Diameter and axial ratio were statistically different after comparison of MHNW vs. MUNW (+0.41 μm, +0.05 μm); MUNW vs. MHO (−0.70 μm, −0.05 μm); and MHO vs. MUO (+0.38 μm, +0.04 μm), respectively. Hypercholesterolemia was associated with larger and more elongated RBC, while obesity with smaller RBC. Besides, age, HDL, ultra-processed food consumption were associated with altered RBC morphology.

Authors

Loyola-Leyva A, Loyola-Rodríguez JP, Figueroa YT, González FJ, Atzori M, et al.

Journal

DOI