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Hypercholesterolemia associated with erythrocytes morphology assessed by scanning electron microscopy in metabolically unhealthy individuals with normal-weight and obesity
Associate hypercholesterolemia and obesity with red blood cell (RBC) morphology as assessed by scanning electron microscopy (SEM) in metabolically healthy and unhealthy adults with normal weight and with obesity.
SEM images showed altered RBC morphologies in the MUNW, MHO, and MUO groups. Diameter and axial ratio were statistically different after comparison of MHNW vs. MUNW (+0.41 _m, +0.05 _m); MUNW vs. MHO (_0.70 _m, _0.05 _m); and MHO vs. MUO (+0.38 _m, +0.04 _m), respectively. Hypercholesterolemia was associated with larger and more elongated RBC, while obesity with smaller RBC. Besides, age, HDL, ultra-processed food consumption were associated with altered RBC morphology.
Loyola-Leyva A, Loyola-Rodríguez JP, Figueroa YT, González FJ, Atzori M, et al.