Data

Year of publication

2021

Type

Quantitative

Design

Cross-sectional

Classification

NOVA

Country studied

Iran

Data

Primary

Data Collected

One food frequency

Study setting

Non-stated

Age group of participant

Teenagers/13-19

Participant sex

Mixed

Target population

Vulnerable (Teenagers)

Sample size

n= 139 (participants)

Higher ultra-processed food intake is associated with higher DNA damage in healthy adolescents

Goal

Assess ultra-processed food intake and its association with urinary levels of 8-hydroxy-20-deoxyguanosine (8-OHdG), a biomarker of DNA oxidative damage, in 139 healthy adolescents in Karaj City in Iran.

Results

Adolescents in the higher tertile of ultra-processed food consumption had a significantly higher mean level of urinary 8-OHdG/creatinine in comparison with the lower tertiles in the crude model (Pfor trend: 0·003) and after adjustment for confounding variables, including total energy intake, sex, age, BMI for age Z-score, obesity and physical activity (Pfor trend: 0·004). This asso- ciation was still significant after adjusting for dietary intake of whole grains, nuts, legumes, the ratio of MUFA:SFA (g/d) and Mediterranean dietary score (Pfor trend: 0·002). More studies are needed to explore the determinants of ultra-processed food supply, demand, consumption and health effects; such studies should be applied to develop evidence-informed policies and regulatory mechanisms to improve children’s and adolescents’ food environment policymaking and legislation with special attention to ultra-processed food.

Authors

Edalati S, Bagherzadeh F, Asghari Jafarabadi M, Ebrahimi-Mamaghani M.

Journal

British Journal of Nutrition

DOI