Data

Year of publication

2020

Type

Quantitative

Design

Cross-sectional

Classification

NOVA

Country studied

Spain

Data

Primary

Data Collected

One food frequency

Study setting

Clinic

Age group of participant

Adults/40-60

Participant sex

Male

Target population

Vulnerable

Sample size

n=1876 (participants)

High consumption of ultra-processed food may double the risk of subclinical coronary atherosclerosis: the Aragon Workers’ Health Study (AWHS)

Goal

Assess whether consumption of UPF is directly associated with subclinical coronary atherosclerosis in middle-aged men.

Results

No coronary calcium was detected in 60.2% of the participants, whereas 10.2% had a CACS_≥_100. A significant dose-response association was observed between energy-adjusted UPF consumption and the risk of having a CACS_≥_100, when compared with those in the lowest CACS categories (CACS of 0 together with CACS_>_0 and <_100). The fully adjusted ORs (95% CI) of having a CACS_≥_100 across quartiles of energy-adjusted UPF consumption (approximately 100_g/day in the lowest quartile (ref.) and 500_g/day in the highest) were 1.00 (ref.), 1.50 (0.93, 2.42), 1.56 (0.96, 2.52), and 2.00 (1.26, 3.16), p trend .005.

Authors

Montero-Salazar H, Donat-Vargas C, Moreno-Franco B, et al.

Journal

BMC Med

DOI