Data

Year of publication

2020

Type

Qualitative

Design

Narrative

Classification

Other (non-stated)

Country studied

Global

Data

Secondary

Data Collected

Literature

Study setting

Online

Age group of participant

N/A

Participant sex

N/A

Target population

General

Sample size

N/A

Food additives containing nanoparticles induce gastrotoxicity, hepatotoxicity and alterations in animal behavior: The unknown role of oxidative stress./Food and Chemical Toxicology

Goal

Analyze the evidence of gastrotoxicity, hepatotoxicity and the impact of microbiota on gut-brain and gut-liver axis induced by titanium dioxide (E171), iron oxides and hydroxides (E172), silver (E174), and gold (E175) are highly used as colorants while silicon dioxide (E551) and their non-food grade nanosized counterparts after oral consumption.

Results

These food additives induce gastrotoxicity, hepatotoxicity and alterations in gut microbiota and most evidence points out oxidative stress as the main mechanism of toxicity, however, the role of oxidative stress as the main mechanism needs to be explored further.

Authors

Medina-Reyes EI, Rodríguex-Ibarra C, Déciga-Alcaraz A, Diaz-Urbina D, Chirino YI, Pedraza-Chaverri J.

Journal

DOI