Year of publication
One food frequency questionnaire, three food records
Age group of participant
Diet quality is associated with cardiometabolic outcomes in survivors of childhood leukemia/Nutrients
Explore the associations between diet quality indices, cardiometabolic health indicators and inflammatory biomarkers among childhood acute lymphoblastic leukemia (cALL) survivors.
We found that 88% of adults and 46% of children adhered poorly to the Mediterranean diet, 36.9% had poor adherence to the World Health Organisation (WHO) recommendations and 76.3% had a diet to be improved according to the HEI-2015 score. On average, ultra-processed foods accounted for 51% of total energy intake. Low HDL-C was associated with a more inflammatory diet (E-DIITM score) and higher intake of ultra-processed foods. A greater E-DII score was associated with elevated insulin resistance (HOMA-IR), and consumption of ultra-processed foods was correlated with high triglycerides. Circulating levels of TNF-α, adiponectin and IL-6 were influenced by diet quality indices, while CRP and leptin were not. In conclusion, survivors of cALL have poor adherence to dietary recommendations, adversely affecting their cardiometabolic health.
Bérard S, Morel S, Teasdale E, Shivappa N, Hebert Jr, et al.