Data

Year of publication

2018

Type

Quantitative

Design

Longitudinal

Classification

NOVA

Country studied

France

Data

Secondary

Data Collected

Minimum two 24 hours recalls (mean= 5,4)

Study setting

Online

Age group of participant

Adults/18-72,8

Participant sex

Mixed

Target population

General

Sample size

n=104 980 (participants)

Consumption of ultra-processed foods and cancer risk: results from NutriNet-Santé prospective cohort

Goal

Assess the prospective associations between consumption of ultra-processed food and risk of cancer.

Results

Ultra-processed food intake was associated with higher overall cancer risk (n=2228 cases; hazard ratio for a 10% increment in the proportion of ultraprocessed food in the diet 1.12 (95% confidence interval 1.06 to 1.18); P for trend<0.001) and breast cancer risk (n=739 cases; hazard ratio 1.11 (1.02 to 1.22); P for trend=0.02). These results remained statistically significant after adjustment for several markers of the nutritional quality of the diet (lipid, sodium, and carbohydrate intakes and/or a Western pattern derived by principal component analysis). Conclusions : In this large prospective study, a 10% increase in the proportion of ultra-processed foods in the diet was associated with a significant increase of greater than 10% in risks of overall and breast cancer. Further studies are needed to better understand the relative effect of the various dimensions of processing (nutritional composition, food additives, contact materials, and neoformed contaminants) in these associations.

Authors

Fiolet, T, Srour, B, Sellem, L, Kesse-Guyot, E, Allès, B, Méjean, C. & al.

Journal

The British Medical Journal

DOI